“It’s crazy,” said Ted Kyle, another poster author, who writes the blog ConscienHealth. “It’s not like you have to do extensive studies with every drug, but at a minimum we should say, ‘Oh, would this be a problem?'”
Regulators do not require drugs to be specifically tested in people with a large amount of body fat, so even if doctors wanted to prescribe a higher dose, they would not know how much to administer or which drugs are most likely to cause harm. ‘be affected, Apovian and others. say the experts.
The Food and Drug Administration, which regulates drug approval and sets requirements for drug trials, recognizes the problem.
He said he hoped workshop participants from the FDA, the University of Maryland and elsewhere would help fill this information gap “to ensure that we move toward appropriate drug dosing in the obese patient.
By jzaqhzmy
